DEEPAK
Dr.  LOKWANI   DEEPAK  KHATUMAL

EDUCATIONAL QUALIFICATIONS

Qualification Subject University/Board Month and Year of Passing Class

CORE COMPETENCY

  • Computer Aided Drug Design and handling of Molecular Modeling Softwares
  • Synthesis of bioactive compounds from milligrams to multi grams scale
  • Designing and synthesis of selective COX-2 inhibitors
  • Purification of small molecule using column chromatography

SUBJECT TAUGHT

Undergraduate Post Graduate
  • Pharmaceutical Medicinal Chemistry - III
  • Pharmaceutical Medicinal Chemistry - I

EMPLOYMENT AND EXPERIENCE

  • ICMR Senior Research Fellow, Department of Chemical Technology, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad from 01/01/2013 to 31/12/2014
  • Project Fellow to UGC Major Research Project, sanction to Prof. Devanand B. Shinde, Department of Chemical Technology, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad from 22/02/2010 to 31/12/2012

RESEARCH PUBLICATIONS

  • W. Doherty, N. Adler, A. Knox, D. Nolan, J. McGouran, A. P. Nikalje, D. K. Lokwani, A. P. Sarkate, P. Evans, Synthesis and Evaluation of 1,2,3-Triazole-Containing Vinyl and Allyl Sulfones as Anti-Trypanosomal Agents, Eur. J. Org. Chem. 2017, 2017, 175. (ISSN: 1099-0690, IF- 3.068 (TJR))
  • V. S. Dofe, A. P. Sarkate, D. K. Lokwani, S. H. Kathwate, C. H. Gill, Synthesis, antimicrobial evaluation, and molecular docking studies of novel chromone based 1,2,3-triazoles, Research on Chemical Intermediates, Available Online (In Press), 2016, (ISSN: Print 0922-6168, online 1568-5675, IF-1.833 (TJR))
  • S. V. Tiwari, J. A. Seijas, M. P. Vazquez-Tato, A. P. Sarkate, D. K. Lokwani, A. P. G. Nikalje, Ultrasound Mediated One-Pot, Three Component Synthesis, Docking and ADME Prediction of Novel 5-Amino-2-(4-chlorophenyl)-7-Substituted Phenyl-8,8a-dihydro-7H-(1,3,4)thiadiazolo(3,2-) pyrimidine-6-carbonitrile Derivatives as Anticancer Agents, Molecules 2016, 21, 894, (ISSN: 1420-3049, IF-2.465 (TJR))
  • A.P. Sarkate, P.R. Murumkar, D.K. Lokwani, A.D. Kandhare, D.B. Shinde, K.G. Bothara, Design of selective TACE inhibitors using molecular docking studies: Synthesis and preliminary evaluation of anti-inflammatory and TACE inhibitory activity, SAR and QSAR in Environmental Research, 2015, 26, 905. (ISSN: Print 1062-936X online 1029-046X; IF-1.897 (TJR))
  • A. P. Sarkate, D. K. Lokwani, S. S. Bahekar, D. B. Shinde, synthesis and docking studies of 2-(nitrooxy) ethyl-4-(2-(substitutedphenyl)-4-(substitutedphenyl)-1h-imidazole-1-yl) benzoate as anti-inflammatory, Analgesic and nitric oxide releasing agents, International Journal of Pharmacy and Pharmaceutical Sciences, 2015, 7, 197, (ISSN: 0975-1491, IF-  0.49 (SJR))
  • D. K. Lokwani R. Azad, A. P. Sarkate, P. Reddanna, D. B. Shinde, Structure Based Library Design (SBLD) for new 1,4-dihydropyrimidine scaffold as simultaneous COX-1/COX-2 and 5-LOX inhibitors, Bioorganic and Medicinal Chemistry, 2015, 23, 4533. (ISSN: 0968-0896, IF-2.923 (TJR))
  • J. N. Sangshetti, D. K. Lokwani, R. S. Chouthe, B. Raval, F. A. Kalam Khan, D. B. Shinde, Green synthesis and biological evaluation of some new benzothiazolo [2,3-b] quinazolin-1-ones as anticancer agents, Medicinal Chemistry Research, 2014, 23, 4893. (ISSN: Print 1054-2523, online 1554-8120, IF-1.436 (TJR))
  • S. N. Mokale, D. K. Lokwani, D. B. Shinde, Synthesis, in-vitro reverse transcriptase inhibitory activity and docking study of some new imidazol-5-one analogs, Medicinal Chemistry Research, 2014, 23, 3752. (ISSN: Print 1054-2523, online 1554-8120, IF-1.436 (TJR))
  • D. K. Lokwani, S. N. Mokale, D. B. Shinde, 3D QSAR studies based in-silico screening of 4,5,6-triphenyl-1,2,3,4-tetrahydropyrimidine analogs for anti- inflammatory activity, European Journal of Medicinal Chemistry 2014, 73, 233. (ISSN: 0223-5234, IF-3.902 (TJR))
  • D. K. Lokwani, A. P. Sarkate, D. B. Shinde, 3D-QSAR and docking studies of benzoyl urea derivatives as tubulin-binding agents for antiproliferative activity, Medicinal Chemistry Research. 2013, 22, 1415. (ISSN: Print 1054-2523, online 1554-8120, IF-1.436 (TJR))
  • D. K. Lokwani, R. Shah, S. N. Mokale, P. Shastry, D. B. Shinde, Development of energetic pharmacophore for the designing of 1,2,3,4-tetrahydropyrimidine derivatives as selective cyclooxygenase-2 inhibitors, Journal of Computer Aided Molecular Design 2012, 26, 267. (ISSN: Print 0920-654X, online 1573-4951, IF-3.199 (TJR))
  • S. N. Mokale, D. K. Lokwani, D. B. Shinde, Synthesis, biological activity and docking study of imidazol-5-one as novel non-nucleoside HIV-1 reverse transcriptase inhibitors, Bioorganic and Medicinal Chemistry, 2012, 20, 3119. (ISSN: 0968-0896, IF-2.923 (TJR))
  • J. N. Sangshetti, D. K. Lokwani, A. P. Sarkate, D. B. Shinde, Synthesis, Antifungal Activity, and Docking Study of Some New 1,2,4-triazole Analogs, Chemical Biology and Drug Design, 2011, 75, 800. (ISSN: 1747-0285, IF- 2.802 (TJR))
  • A. P. Sarkate, D. K. Lokwani, A. A. Patil, et. al., Synthesis and evaluation of anti-inflammatory, analgesic, ulcerogenicity and nitric oxide-releasing studies of novel ibuprofen analogs as nonulcerogenic derivatives, Medicinal Chemistry Research, 2011, 20, 795. (ISSN: Print 1054-2523, online 1554-8120, IF-1.436 (TJR))
  • D. K. Lokwani, S. V. Bhandari, R. Pujari, et. al., Use of Quantitative Structure Activity Relationship (QSAR) and ADMET Prediction Studies as Screening Methods for design of Benzyl Urea Derivatives for Anticancer Activity, Journal of Enzyme Inhibition and Medicinal Chemistry 2011, 26, 319. (Print ISSN: 1475-6366 Online ISSN: 1475-6374 IF-3.428 (TJR)
  • V. S. Pawar, D. K. Lokwani, S. V. Bhandari, K. G. Bothara, T. S. Chitre, T. L. Devale, N. S. Modhave, J. K. Parikh, Design, Docking Study and ADME prediction of Isatin Derivatives as Anti-HIV Agents, Medicinal Chemistry Research, 2011, 20, 370. (ISSN: Print 1054-2523, online 1554-8120, IF-1.436 (TJR))
  • V. S. Pawar, D. K. Lokwani, S. V. Bhandari, D. Mitra, S. Sabde, K. Bothara, A. Madgulkar, Design of Potential Reverse Transcriptase Inhibitor containing Isatin Nucleus Using Molecular Modeling Studies, Bioorganic Medicinal Chemistry, 2010, 18, 3198. (ISSN: 0968-0896, IF-2.923 (TJR))
  • S. V. Bhandari, S. C. Dangre, K. G. Bothara, A. A. Patil, A. P. Sarkate, D. K. Lokwani, S. T. Gore, B. J. Deshmane, V. T. Raparti, C. V. Khachane, Design, Synthesis and Pharmacological Screening of Novel Nitric Oxide Donors Containing1, 5-Diaryl Pyrazolin-3-One as Non Toxic NSAIDs, European Journal of Medicinal Chemistry. 2009, 44, 4622. (ISSN: 0223-5234, IF-3.902, (TJR))
  • S. V. Bhandari, J. K. Parikh, K. G. Bothara, T. S. Chitre, D. K. Lokwani, T. L. Devale, et. al., Design, Synthesis and Evaluation of Anti-inflammatory, Analgesic, Ulcerogenicity and Nitric oxide releasing studies of Novel Indomethacin analogs as Nonulcerogenic Derivatives, Journal of Enzyme Inhibition and Medicinal Chemistry 2010, 25, 520. (Print ISSN: 1475-6366 Online ISSN: 1475-6374, IF-3.428 (TJR))
  • S. V. Bhandari, K. G. Bothara, V. S. Pawar, D. K. Lokwani, T. Devale, Design of new chemicals entities as selective COX–2 inhibitors using structure optimization by molecular modeling studies, Internet Electronic Journal of Molecular Design, 2009, 8, 14. (ISSN: online 1538-6414)

RESEARCH PRESENTATION AT CONFERENCES & SYMPOSIUMS

  • The Prediction of Site of Metabolism (SOM) in ligands, metabolized by CYP3A4 Enzyme: Comparison of Glide XP and Induced Fit Docking (IFD) at Recent Advances in Computational Drug Design, Schrodinger and Indian Institute of Science (IIsc), Bangalore, during 16/09/2013 to 17/09/2013.
  • 3D QSAR and docking studies of benzoyl urea derivatives as tubulin binding agents for antiproliferative activity at National conference on Computational Biology and Chemistry, School of Bio Sciences and Technology, VIT University, Vellore during 02/042012 to 03/04/2012
  • Pharmacophore Optimization of selective protein kinase inhibitors using Molecular modeling studies at 60th Indian Pharmaceutical Congress (IPC), Delhi during 12/12/2008 to 14/12/2008.

PARTICIPATION IN WORKSHOP, SEMINAR AND REFRESHER COURSE

  • International Conference on Drug Design, Schrödinger, Jawaharlal Nehru University, New Delhi during 08/04/2017-09/04/2017
  • New Development in Microwave Technology, Department of Chemical Technology, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad, during 10/09/2013.
  • Interdisciplinary Approaches in Pharmaceutical Research, Y. B. Chavan College of Pharmacy, Aurangabad during 05/03/2012 to 06/03/2012
  • Advances & Trends in Drug Development Process, MAEER’s Maharashtra Institute of Pharmacy, Pune during 05/03/2011 to 07/03/2011
  • Mathematics in Drug Discovery, DST Center for Mathematical Biology, IMI, IISC, Bangalore, Piramal Life Science Limited and NCL, Pune, during 25/09/2010 to 29/09/2010.
  • Recent Advances in Flash Chromatography, Deptartment of Chemical Technology, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad during 17/09/20103
  • 60th Indian Pharmaceutical Congress (IPC), Delhi during 12/12/2008 to 14/12/2008.

CONFERENCE/SEMINAR/WORKSHOPS ORGANISED

  • Worked as a Coordinator at Hands on training programme on Computer Aided Drug Design (CADD) organised by Y. B. Chavan College of Pharmacy, Aurangabad during 06/03/2017 to 12/03/2017
  • Worked as an Organizing Committee Member at National Conference in Pharmaceutical Analysis Organized by Dr. Babasaheb Ambedkar Marathwada University, Aurangabad during 18/10/2013 to 19/10/2013.
  • Worked as an Organizing Committee Member at National Conference in Pharmaceutical Analysis Organized by Dr. Babasaheb Ambedkar Marathwada University, Aurangabad 15/09/2011 to 17/09/2011.

AWARD, RECOGNITION AND SCHOLARSHIP ACHIEVEMENT

  • Received National Prize from CSIR-OSDD-VP for short Video Competition on Topic “The Need of New Drugs for Tuberculosis” Presented during Rastriya Vigyan Chalchitra Mela & Competition 2014 (Title: Brahmashtra, YouTube Link: http://youtu.be/mnO4JXAr8Ko)
  • Received Second Prize for Poster Presentation in National conference on Computational Biology and Chemistry held at School of Bio Sciences and Technology, VIT University, Vellore during 02/042012 to 03/04/2012.
  • Received Outstanding Publication Award by vLife Sciences, Pune in the field of Computer Aided Drug and Molecular Design for research article published in Biooranic and Medicinal. Chemistry 2010, 18, 3198-3211
  • Secured 94.08 percentile in All India Graduate Aptitude Test in Engineering (GATE) and received Junior Research Fellowship from Government of India. All India Rank 1079.

EXTRA CURRICULAR AND SOCIAL ACTIVITIES

  • Participated in CSIR-OSDD-VP for short Video Competition on Topic “The Need of New Drugs for Tuberculosis” Presented during Rastriya Vigyan Chalchitra Mela & Competition 2013
  • Runner of Chess Competition conducted on annual day celebration 2007 at Sudhakarrao Naik Institute of Pharmacy, Pusad
  • Participant of runner team in Cricket Championship conducted on annual day celebration 2007 at Sudhakarrao Naik Institute of Pharmacy, Pusad
  • Participant of Best Fashion Show conducted on annual day celebration 2007 at Sudhakarrao Naik Institute of Pharmacy, Pusad
  • Participant of Best Musical Script conducted on annual day celebration 2007 at Sudhakarrao Naik Institute of Pharmacy, Pusad
  • Participate in Sub-Institute level in National Quiz, ”Awakening Indians to India” conducted by All India Chinmaya Yuva Kendra 2003-2004

PHARMACITS REGISTRATION

  • Registered Pharmacist with Maharashtra State Pharmacy Council, Mumbai (Registration No. 84480)

ADMINISTRATIVE RESPONSIBILITIES

  • Information and Communication Technology Cell Member

UNIVERSITY ASSIGNMENTS


Contact:

Email:-   dklokwani@gmail.com
Department:- Pharmaceutical Chemistry
Mobile:- 9372593591